![]() ![]() One older study in 221 people, 112 of whom had diabetes-related foot infections, found that those with severe vitamin D deficiency were more likely to have higher levels of inflammatory markers that can jeopardize healing ( 31). Vitamin D’s role in controlling inflammation and addressing infections may also be important for proper healing. One review of four studies found that vitamin D deficiency compromised certain aspects of healing in people who had dental surgery ( 30). In fact, results from a test-tube study suggest that vitamin D increases the production of compounds that are crucial for forming new skin as part of the wound-healing process ( 29). Slow wound healing after surgery or injury may be a sign that your vitamin D levels are too low. Still, more research is needed to understand the relationship between vitamin D and depression. The effects of vitamin D supplements have been mixed, but some reviews have found that they helped relieve symptoms of depression ( 25, 26, 27, 28). Vitamin D deficiency has been linked to depression, especially in older adults - although some study results are conflicting ( 22, 23, 24). However, a large research review found that this association was inconsistent across other similar studies ( 19, 20).Ī review of 81 studies also found that people with arthritis, muscle pain, and chronic widespread pain tended to have lower levels of vitamin D than people without these conditions ( 21). One study in 98 adults with lower back pain linked lower levels of vitamin D to more severe pain. Vitamin D helps maintain bone health by improving your body’s absorption of calcium. Bone and back painīone and lower back pain may be symptoms of inadequate vitamin D levels ( 17, 18). Interestingly, several studies show that supplementing with this vitamin may reduce the severity of fatigue in people with a deficiency ( 15, 16).Īll the same, more research is needed. What’s more, 89% of the participants were deficient in this vitamin ( 14). One observational study in female nurses also found a strong connection between low vitamin D levels and self-reported fatigue. Plus, a study in 39 children associated low vitamin D levels with poor sleep quality, shorter sleep duration, and delayed bedtimes ( 13). One study in 480 older adults linked vitamin D deficiency with fatigue symptoms ( 12). Unlike more visible causes like stress, depression, and insomnia, vitamin D deficiency is often overlooked as a potential cause of fatigue. Fatigue and tirednessįeeling tired can stem from a number of causes, one of which may be vitamin D deficiency. However, it is important to note that taking vitamin D supplements - at any dosage - will not prevent COVID-19 ( 2). Recently, vitamin D deficiency has been linked to an increased risk of COVID-19, as well as an increased risk of experiencing severe effects from the condition. Several large observational studies have shown a link between a deficiency and respiratory tract infections such as colds, bronchitis, and pneumonia ( 7, 8).Ī number of studies have found that taking up to 4,000 IU of vitamin D daily may reduce the risk of respiratory tract infections ( 9, 10, 11). If you often become sick, especially with colds or the flu, low vitamin D levels may be a contributing factor. Vitamin D directly interacts with the cells that are responsible for addressing infections ( 6). One of the most important roles of vitamin D is supporting immune health, which helps you ward off viruses and bacteria that cause illness. Keeping that in mind, it’s still helpful to know what signs and symptoms to look for. Sometimes, you may have no symptoms at all. Vitamin D deficiency can be difficult to notice because symptoms may not occur for several months or years. ![]() Signs and symptoms of vitamin D deficiency
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