On standard, full-sized keyboards, the applications key is usually found on the same row as the space bar, and it is located to the right of the space bar between the right side Windows key and the right side control key. However, it is an incredibly useful key for those who use screen readers to access the computer. If you’re asking your self, “Have you ever heard of the applications key, much less used it? Nope, didn’t think so!” Then you are like most people I know and have worked with. The applications/menu key!?!? Never heard of it! So, what can they do? The answer is simple: use the applications, or menu key! However, if I am working with my auditory and tactual computer users, that is those who use screen readers and keyboards/braille displays for input access, they don’t necessarily have the benefit of knowing where the mouse is to move it to an icon and then right click this approach is visual. ![]() Now, this method of accessing the context menu when needed is good for me, and it will likely work well for my students who are visual computer users like me. Get it? What I click on is the… context! For example, when I click on a desktop icon, I will open up the icon’s context menu that shows menu options like “Open,” “Delete,” or “Properties.” You will find an image of this context menu below. When I do so, I open up what is called the “context menu” for what I just clicked on. One of the most common functions I will use the mouse and cursor for is to move it over something, like an icon or a link, and then right click. To illustrate the importance of pneumococcal colonisation in relation to pneumococcal disease and prevention of disease, we discuss the mechanism and epidemiology of colonisation, the complexity of relations within and between species, and the consequences of the different preventive strategies for pneumococcal colonisation.As a visual user of the computer, I use a mouse to move a visual cursor around the screen to click on different items on the screen. Another important issue is whether the aim should be to prevent pneumococcal disease by eradication of nasopharyngeal colonisation, or to prevent bacterial invasion leaving colonisation relatively unaffected and hence preventing the occurrence of replacement colonisation and disease. Several surface-associated protein vaccines are currently under investigation. Therefore, the search for new vaccine candidates that elicit protection against a broader range of pneumococcal strains is important. However, vaccine coverage is limited, and replacement by non-vaccine serotypes resulting in disease is a serious threat for the near future. The current seven-valent conjugate vaccine is highly effective against invasive disease caused by the vaccine-type strains. ![]() Pneumococcal disease is preceded by asymptomatic colonisation, which is especially high in children. ![]() The treatment of pneumococcal infections is complicated by the worldwide emergence in pneumococci of resistance to penicillin and other antibiotics. The burden of disease is highest in the youngest and oldest sections of the population in both more and less developed countries. Streptococcus pneumoniae is an important pathogen causing invasive diseases such as sepsis, meningitis, and pneumonia.
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